Team also known as
- Cleveland Indians 1915-2021
- 5 prior teams 1894-1914
Cleveland Guardians as Primary Team
- Roberto Alomar, 2nd Baseman, 1999-2001, Class of 2011
- Earl Averill, Center Fielder, 1929-1939, Class of 1975
- Lou Boudreau, Shortstop, 1938-1950, Class of 1970
- Steve Carlton, Pitcher, 1987, Class of 1994
- Stan Coveleski, Pitcher, 1916-1924, Class of 1969
- Larry Doby, Center Fielder, 1947-1955, 1958, Class of 1998
- Bob Feller, Pitcher, 1936-1941, 1945-1956, Class of 1962
- Elmer Flick, Right Fielder, 1902-1910, Class of 1963
- Addie Joss, Pitcher, 1902-1910, Class of 1978
- Nap LaJoie, 2nd Baseman, 1902-1914, Class of 1937
- Bob Lemon, Pitcher, 1941-1942, 1946-1958, Class of 1976
- Hal Newhouser, Pitcher, 1954-1955, Class of 1992
- Joe Sewell, Shortstop, 1920-1930, Class of 1977
- Tris Speaker, Center Fielder, 1916-1926, Class of 1937
- Jim Thome, 1st Baseman, 1991-2002, 2011, Class of 2018
- Early Wynn, Pitcher, 1949-1957, 1963, Class of 1972
Hall of Famers who also played for the Cleveland Guardians
- Harold Baines, Designated Hitter, 1999, Class of 2019
- Gaylord Perry, Pitcher, 1972-1975, Class of 1991
- Joe Gordon, 2nd Baseman, 19347-1950, Class of 2009
- Ralph Kiner, Left Fielder, 1955, Class of 1975
- Al López, Manager, 1951-1956, Class of 1977
- Minnie Miñoso, Left Fielder, 1949, 1951,1958-1959, Class of 2022
- Jack Morris, Pitcher, 1994, Class of 2018
- Eddie Murray, 1st Baseman, 1994-1996, Class of 2003
- Phil Niekro, Pitcher, 1986-1987, Class of 1997
- Satchel Paige, Pitcher, 1941-1947, Class of 1971
- Frank Robinson, Right Fielder, 1974-1976, Class of 1982
- Hoyt Wilhelm, Pitcher, 1957-1958, Class of 1985
- Dave Winfield, Right Fielder, 1995, Class of 2001
- Cy Young, Pitcher, 1909-1911, Class of 1937
Carolina Panthers in the Hall of Fame
Reggie White, Defensive End, 2000, Class of 2006