Houston Astros as Primary Team
- Jeff Bagwell, 1st Baseman, 1991-2005, Class of 2017
- Craig Biggio, 2nd Baseman, 1988-2007, Class of 2015
Hall of Famers who also played for the Houston Astros
- Leo Durocher, Manager, 1972-1973, Class of 1994
- Nellie Fox, 2nd Baseman, 1964-1965, Class of 1997
- Randy Johnson, Pitcher, 1998, Class of 2015
- Eddie Mathews, 3rd baseman, 1967, Class of 1978
- Joe Morgan, 2nd Baseman, 1963-1971, 1980, Class of 1990
- Robin Roberts, Pitcher, 1965-1966, Class of 1976
- Iván Rodríguez, Catcher, 2009, Class of 2017
- Nolan Ryan, Pitcher, 1980-1988, Class of 1999
- Don Sutton, Pitcher, 1981-1982, Class of 1998
Carolina Panthers in the Hall of Fame
Reggie White, Defensive End, 2000, Class of 2006